Magnesium Glycinate vs Bisglycinate-Are They the Same?

19 July 2025
Written By fitnesstoday.us

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Discover if magnesium glycinate and bisglycinate are the same supplement. Compare top brands like Thorne, Naturelo, and more in this comprehensive guide.

Magnesium Glycinate vs Bisglycinate: The Complete Guide

If you’ve been browsing Reddit for magnesium supplement recommendations, you’ve likely encountered two very similar-sounding terms: magnesium glycinate and magnesium bisglycinate. The confusion is understandable, and you’re not alone in wondering whether these are different supplements or just different names for the same thing.

This comprehensive guide will clear up the confusion once and for all. We’ll explore the relationship between these two forms, examine popular brands like Naturelo and Thorne, and provide essential information for people with specific health conditions like myasthenia gravis. Whether you’re a first-time supplement buyer or looking to switch brands, this article will help you make an informed decision.

Understanding the difference between these magnesium forms becomes especially important when you’re investing in your health. With so many brands and formulations available, knowing exactly what you’re purchasing can save you money and ensure you’re getting the right supplement for your needs.

Magnesium Glycinate vs Bisglycinate: Are They the Same?

Understanding Magnesium Glycinate and Bisglycinate

The short answer to the main question is simple: magnesium glycinate and magnesium bisglycinate are the same compound. The terms are used interchangeably to describe magnesium that has been chelated (bound) to two molecules of the amino acid glycine.

The “bis” in bisglycinate literally means “two,” referring to the two glycine molecules attached to each magnesium ion. Some manufacturers prefer using “glycinate” while others use “bisglycinate,” but both describe identical chemical structures. This naming variation often causes confusion among consumers, leading to the frequent Reddit discussions about their differences.

Why the Different Names?

The naming inconsistency stems from different manufacturing and marketing preferences. European manufacturers tend to favor “bisglycinate,” while American companies often use “glycinate.” Both forms offer the same benefits: superior absorption compared to other magnesium forms and reduced likelihood of digestive upset.

Chemical Structure and Absorption

Chelated magnesium forms like glycinate/bisglycinate are designed to improve bioavailability. The amino acid glycine acts as a protective carrier, helping the magnesium pass through the intestinal wall more efficiently. This process bypasses the common absorption issues associated with cheaper magnesium forms like oxide or sulfate.

Popular Brand Comparisons

Naturelo Magnesium Glycinate Chelate

Naturelo positions itself as a premium supplement brand, and their naturelo magnesium glycinate chelate formula reflects this commitment to quality. Their product features:

  • Chelated magnesium for enhanced absorption
  • Third-party testing for purity
  • Vegetarian capsules
  • No artificial additives or fillers

Users on Reddit frequently praise Naturelo for consistent quality, though some note the higher price point compared to generic alternatives.

BetterVits Magnesium Glycinate

Bettervits magnesium glycinate has gained attention as a more budget-friendly option without sacrificing quality. Key features include:

  • Competitive pricing per serving
  • Good bioavailability
  • Positive user reviews for sleep improvement
  • Straightforward ingredient profile

Thorne Magnesium Glycinate Powder

Magnesium glycinate powder thorne represents the gold standard for many healthcare practitioners. Thorne’s reputation in the professional supplement market makes their products popular among those seeking pharmaceutical-grade quality:

  • NSF certification for sport
  • Extensive third-party testing
  • Powder form allows for flexible dosing
  • Preferred by many functional medicine doctors

Organics Ocean Products

The brand offers several magnesium formulations, including organics ocean magnesium glycinate maximum strength and organics ocean pure magnesium glycinate with zinc. Their products focus on:

  • Higher potency formulations
  • Combination supplements with complementary minerals
  • Organic certification where applicable

Reddit users have mixed reviews, with some praising the potency while others prefer single-ingredient formulations.

Special Considerations for Myasthenia Gravis

The relationship between magnesium glycinate and myasthenia gravis requires careful consideration. Myasthenia gravis is an autoimmune condition affecting the communication between nerves and muscles, and magnesium supplementation can have complex effects.

Potential Benefits

Some individuals with myasthenia gravis report improvements in:

  • Muscle cramping
  • General fatigue
  • Sleep quality
  • Stress management

Important Precautions

However, myasthenia gravis and magnesium glycinate interaction isn’t straightforward. Magnesium can potentially:

  • Interfere with certain medications used to treat MG
  • Affect neuromuscular transmission
  • Impact the effectiveness of cholinesterase inhibitors

Critical Note: Anyone with myasthenia gravis should consult their neurologist before starting any magnesium supplement. The condition’s complexity requires medical oversight when introducing new supplements.

Reddit Community Insights

The innate vitality magnesium glycinate reddit discussions reveal interesting patterns in user preferences. Reddit communities like r/Supplements and r/Nootropics frequently discuss:

Most Recommended Brands

  1. Thorne (for quality)
  2. Life Extension (for value)
  3. Doctor’s Best (for affordability)
  4. Naturelo (for clean ingredients)

Common User Experiences

  • Most users notice improved sleep within 1-2 weeks
  • Digestive tolerance is generally excellent
  • Timing matters: evening doses work best for most people
  • Powder forms allow for easier dose adjustment

Red Flags Mentioned by Users

  • Extremely cheap products often contain fillers
  • Some brands use magnesium oxide blends despite labeling
  • Third-party testing certificates aren’t always readily available

Wholesale and Sourcing Information

For those interested in magnesium glycinate wholesale or magnesium glycinate suppliers, the market offers various options. Professional magnesium glycinate supplier companies typically require:

  • Business licenses for wholesale accounts
  • Minimum order quantities
  • Quality certifications and testing documentation

Key wholesale suppliers include:

  • Albion Minerals (creator of original Albion chelated minerals)
  • NOW Foods (bulk and private label options)
  • Jarrow Formulas (professional-grade options)

When sourcing from magnesium glycinate suppliers, verify:

  • Certificate of analysis for each batch
  • Heavy metal testing results
  • Proper storage and handling procedures
  • Regulatory compliance documentation

Choosing the Right Product

For Sleep and Relaxation

Look for products providing 200-400mg of elemental magnesium, taken 30-60 minutes before bedtime. Powder forms like Thorne allow for precise dosing adjustments.

For General Health Maintenance

A standard 200mg dose with dinner often provides sufficient supplementation without causing digestive upset.

For Athletic Performance

Higher doses (400-600mg) may be beneficial, but should be divided throughout the day to optimize absorption.

Quality Indicators to Look For

  • Third-party testing certificates
  • Albion or other recognized chelation processes
  • Minimal excipients and fillers
  • Proper packaging to prevent moisture exposure

Combination Products and Added Ingredients

Many manufacturers offer magnesium glycinate with zinc made in usa formulations. These combinations can be beneficial since both minerals support:

  • Immune system function
  • Sleep quality
  • Muscle recovery
  • Stress response

However, be aware that zinc can compete with magnesium for absorption when taken in large amounts simultaneously.

Popular Combinations Include:

  • Magnesium + Zinc (for immune support)
  • Magnesium + Vitamin D3 (for bone health)
  • Magnesium + B-complex (for energy metabolism)
  • Magnesium + Melatonin (for sleep support)

Where to Buy Quality Magnesium Supplements

When searching ocean magnesium glycinate where to buy, consider these reliable sources:

Online Retailers

  • Amazon (verify seller credentials)
  • iHerb (extensive international shipping)
  • Vitacost (competitive pricing)
  • Thrive Market (organic focus)

Physical Stores

  • Whole Foods (curated selection)
  • Local health food stores (personalized service)
  • Costco (bulk options for popular brands)
  • CVS/Walgreens (convenience, limited selection)

Direct from Manufacturer

  • Often provides freshest products
  • Access to bulk options
  • Better customer service for issues
  • Subscription discounts available

Frequently Asked Questions

Is magnesium bisglycinate the same as magnesium glycinate?

Yes, these terms refer to the identical chemical compound. The naming difference is purely semantic, with both describing magnesium chelated to two glycine molecules.

What’s the best time to take magnesium glycinate?

Most people benefit from taking magnesium glycinate in the evening, 30-60 minutes before bedtime. This timing maximizes its relaxation and sleep-promoting effects.

Can I take magnesium glycinate with other supplements?

Generally yes, but spacing is important. Take calcium separately (different meal) as it can compete for absorption. Iron supplements should also be taken at different times.

How much magnesium glycinate should I take daily?

Most adults benefit from 200-400mg of elemental magnesium daily. Start with a lower dose and increase gradually to assess tolerance.

Are there any side effects of magnesium glycinate?

Magnesium glycinate is generally well-tolerated. Rarely, some people may experience mild digestive upset or drowsiness, especially when first starting supplementation.

For those looking to enhance their overall wellness routine, you might also be interested in exploring natural remedies for glowing skin that can complement your supplement regimen.

Making Your Final Decision

Choosing the right magnesium supplement doesn’t have to be complicated. Remember that magnesium glycinate and magnesium bisglycinate are the same compound, so focus on finding a reputable brand that fits your budget and quality requirements.

Consider factors like third-party testing, manufacturing practices, and user reviews when making your decision. Whether you choose Thorne’s pharmaceutical-grade powder, Naturelo’s clean formulation, or a budget-friendly option like BetterVits, the most important factor is consistency in taking your chosen supplement.

Start with a moderate dose, monitor your body’s response, and adjust as needed. If you have specific health conditions like myasthenia gravis, always consult with your healthcare provider before beginning any new supplement regimen.

The journey to better health through proper supplementation is a marathon, not a sprint. Choose a high-quality magnesium glycinate supplement that you can take consistently, and give it time to work. Most users notice improvements in sleep quality and stress management within 2-4 weeks of consistent use.

Your investment in quality magnesium supplementation today can pay dividends in improved sleep, reduced stress, and better overall health for years to come.

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